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Thyroid disorders explained

Hypothyroidism; Hyperthyroidism; Thyroid nodules and swellings; Diagnosing thyroid disorders; Prevention; Thyroid disorders and pregnancy

Women are more likely than men to suffer from thyroid problems, which can cause depression and tiredness

The thyroid is a butterfly-shaped gland you can feel at the base of your neck, just below your Adam's apple. Two lobes - the butterfly 'wings' - fit to either side of your windpipe. This gland is one of the most important in your body as one of the hormones it produces regulates the body's metabolism.

The thyroid gland is a manufacturing and storage facility for thyroid hormone, which is often referred to as the body's metabolic hormone. Among other actions, thyroid hormone stimulates enzymes that combine oxygen and glucose, a process that increases the basal metabolic rate and body heat production. Thyroid hormone also helps maintain blood pressure, regulates tissue growth and development, is critical for skeletal and nervous system development and plays an important role in the maturing of the reproductive system.

Women are five to ten times more likely than men to have thyroid dysfunction and some types of thyroid disease run in families. Although many women get thyroid disorders, doctors often fail to recognise it because the wide variety of symptoms are similiar to other illnesses.

Disorders of the thyroid

  • Hypothyroidism, where the thyroid releases too little hormone so the body's metabolism goes too slowly.
  • Hyperthyroidism, where the thyroid releases too much hormone and the body's metabolism goes too fast.
  • Thyroid nodules and swellings. The tissue of the thyroid can overgrow, resulting in a nodule, or small lump, in part of the gland. Some of the lumps can be active while others are inactive. A small percentage of the inactive lumps may be cancerous.


  • Hypothyroidism
    Hypothyroidism means that the thyroid gland is producing too little hormone. It's a common condition, occurring usually in the second half of life with 90 per cent of the sufferers being female. Hypothyroidism often goes undiagnosed for years because its signs and symptoms can easily be mistaken for other conditions.

    The leading cause of hypothyroidism is called Hashimoto's thyroiditis. Named after the Japanese doctor who first described it in detail, Hashimoto's thyroiditis is an autoimmune disease. This means that the immune system is working against the thyroid - so it's actually producing antibodies to the gland as if it were a foreign substance that needed to be destroyed. The damage caused by the antibodies results in decreased production of thyroid hormone.

    Hypothyroidism may also result from medical treatment of an overactive thyroid gland, which may be with radioactive substances or by surgery. It can also occur during or after pregnancy.

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    This iVillage Health service area is designed for educational purposes only. You should not rely on this information as a substitute for personal medical attention, diagnosis or hands-on treatment. If you are concerned about your health or that of a child, please consult your family's health provider immediately and do not wait for a response from our professionals. For the full Disclaimer, click here.
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