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Breastfeeding and drugs: a mother's guide

by Dr Howard Lee
continued from page 2
breast milk and the most important parameter that determines drug penetration into breast milk) and half-life (an indication of the length of time a drug remains within the body) all affect how much of the drug is transferred into the breast milk.General rules
There are some general guidelines for taking drugs while breastfeeding:
  • Only if you really need it.
  • If you have a choice, delay the start time until your baby is older.
  • Take the lowest possible dose for the shortest possible time.
  • Avoid 'sustained release' drugs.
  • Schedule the doses so that the lowest amount gets into the milk - taking it soon after feeding, preferably a night feed.
  • Watch for any reaction/side effects: mothers are often not informed, and do not realise, that diarrhoea, constipation, sedation or weakness may be a medication problem. Being forewarned will safeguard the baby
Drugs guide
  • Steroids have been safely used in breastfeeding mothers for many years.
  • Most antibiotics are safe.
  • Combined oral contraceptives are contraindicated.
  • Progesterone-only pills are safe.
  • Antidepressants are used with caution. A balance has to be made between the needs of the breastfeeding mother against the possible adverse effects on the infant. These drugs have not been investigated in a controlled and systematic way; there are single case reports and confoundable data, and this makes guidelines difficult.
  • Lithium is not safe.
  • Antiepileptics have not been proven unsafe.
  • Oral anticoagulants (blood-thinning agents) appear safe.
  • All drugs of abuse are contraindicated.


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